__________ Stuart A. Newman __________
Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York 10595, USA.
Main research focus: cellular and molecular mechanisms of vertebrate limb development; physical mechanisms of morphogenesis; mechanisms of morphological evolution; social and cultural implications of biological research and technology.
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Müller, G.B./Newman, S.A., eds. 2003.
Origination of Organismal Form. Beyond the Gene in Developmental and Evolutionary Biology.
Cambridge: MIT Press.
Newman, S.A./Müller, G.B. 2001.
Epigenetic mechanisms of character origination.
In
Wagner, The Character Concept in Evolutionary Biology,
559579.
Originally published 2000 in Journal of Experimental Zoology (Molecular and Developmental Evolution) 288: 304317.
Keywords:
character origination
epigenetic mechanisms.
Newman, S.A./Müller, G.B. 2000. Epigenetic mechanisms of character origination.
Journal of Experimental Zoology (Molecular and Developmental Evolution)
288:
304317.
Reprinted In Wagner, The Character Concept in Evolutionary Biology, 559579.
Keywords:
character origination
epigenetic mechanisms.
Müller, G.B./Newman, S.A.
1999. Generation, integration, autonomy: Three steps in the evolution of homology. In "Homology" (Novartis Foundation Symposium 222), 6579.
Keywords:
development
epigenetic
homology
innovation.
Newman, S.A. 1998.
Epithelial morphogenesis: A physico-evolutionary interpretation.
In
Chuong, Molecular Basis of Epithelial Appendage Morphogenesis,
341358.
Newman, S.A. 1998.
Networks of extracellular fibers and the generation of morphogenetic forces.
In
Beysens/Forgacs, Dynamical Networks in Physics and Biology,
139148.
Newman, S.A./Cloître, M./Allain, C./Forgacs, G./Beysens, D. 1997. Viscosity and elasticity during collagen assembly in vitro: Relevance to matrix-driven translocation.
Biopolymers
41:
337347.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1996. Sticky fingers: Hox genes and cell adhesion in vertebrate limb development.
BioEssays
18:
171174.
Newman, S.A./Tomasek, J.J. 1996.
Morphogenesis of connective tissues.
In
Comper, Extracellular Matrix,
335369.
Downie, S.A./Newman, S.A. 1995. Different roles for fibronectin in the generation of fore and hind limb precartilage condensations.
Develomental Biology
172:
519530.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1995.
Interplay of genetics and physical processes of tissue morphogenesis in development and evolution: The biological fifth dimension.
In
Beysens/Forgacs/Gaill, Interplay of Genetic and Physical Processes in the Development of Biological Form,
312.
Newman, S.A. 1995.
Carnal boundaries: The commingling of flesh in theory and practice.
In
Birke/Hubbard, Reinventing Biology,
191227.
Downie, S.A./Newman, S.A. 1994. Morphogenetic differences between fore and hind limb precartilage Mesenchyme: Relation to mechanisms of skeletal pattern formation.
Develomental Biology
162:
195208.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Forgacs, G./Newman, S.A. 1994. Phase Transitions, Interfaces, and Morphogenesis in a Network of Protein Fibers.
Int. Rev. Cytol.
150:
139148.
Forgacs, G./Newman, S.A./Polikova, Z./Neumann, A.W. 1994. Critical Phenomena in Model Biological Tissues.
Coll. Surf B
3:
139146.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1994. Generic physical mechanisms of tissue morphogenesis: A common basis for development and evolution.
Journal of Evolutionary Biology
7:
467488.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Khan, M.Y./Leonard, C.M./Newman, S.A. 1993. Activation of a heparin-degrading enzyme by a 'Protein Matrix' effect.
Biochem. Molec. Biol. Internat.
30:
579587.
Keywords:
biochemistry
molecular biology.
Newman, S.A. 1993. Is segmentation generic?
BioEssays
15:
277283.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1993.
Why does a limb look like a limb?
In
Fallon et al., Limb Development and Regeneration,
8998.
Newman, S.A./Forgacs, G. 1993.
Generic physical mechanisms in the production of biological form and pattern.
In
Beysens/Boccara/Forgacs, Dynamical Phenomena at Interfaces,
8598.
Newman, S.A. 1992. Generic physical mechanisms of morphogenesis and pattern formation as determinants in the evolution of multicellular organization.
Journal of Bioscience (India)
17:
193215.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1992.
Generic physical mechanisms of morphogenesis and pattern formation as determinants in the evolution of multicellular organization.
In
Mittenthal/Baskin, The Principles of Organization in Organisms,
241267.
Forgacs, G./Newman, S.A./Obukhov, S.P./Birk, D.E. 1991. Phase Transition and Morphogenesis in a Model Biological System.
Phys. Rev. Lett.
67:
23992402.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Hall, B.K./Newman, S.A., eds. 1991.
Cartilage: Molecular Aspects.
Boca Raton: CRC Press.
Khan, M.Y./Newman, S.A. 1991. The saltingout behavior of human plasma fibronectin and its possible correlation with heparin-induced cryoprecipitation of the protein.
Biochem. Internat.
23:
17.
Keywords:
biochemistry
molecular biology.
Khan, M.Y./Newman, S.A. 1991. A rapid colorimetric assay for heparinase activity.
Anal. Biochem.
196:
373376.
Keywords:
biochemistry
molecular biology.
Leonard, C.M./Fuld, H.M./Frenz, D.A./Downie, S.A./Massagué, J./Newman, S.A. 1991. Role of transforming growth factoröß in chondrogenic pattern formation in the developing limb: Stimulation of mesenchymal condensation and fibronectin gene expression by exogenous TGFöß and evidence for endogenous TGFößölike activity.
Develop. Biol.
145:
99109.
[abstract]
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1990.
Dynamical aspects of cell-matrix interactions.
In
Mishra, Molecular and Biological Physics of the Living State,
281293.
Newman, S.A. 1990.
Genetic engineering cannot cure Inherited diseases.
In
Dudley, Genetic Engineering,
8693.
Newman, S.A./Comper, W.D. 1990. 'Generic' physical mechanisms of morphogenesis and pattern formation.
Development
110:
118.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Forgacs, G./Jaikaria, N.S./Frisch, H.L./Newman, S.A. 1989. Wetting, Percolation and Morphogenesis in a Model Tissue System.
J. Theoret. Biol.
140:
417430.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Frenz, D.A./Akiyama, S.K./Paulsen, D.F./Newman, S.A. 1989. Latex Beads as Probes of Cell Surface Extracellular Matrix Interactions During Chondrogenesis: Evidence for a Role for Amino-Terminal Heparin-Binding Domain of Fibronectin.
Developmental Biology
136:
8796.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Frenz, D.A./Jaikaria, N.S./Newman, S.A. 1989. The Mechanism of Precartilage Mesenchymal Condensation. A Major Role for Interaction of the Cell Surface with the Amino-Terminal Heparin-Binding Domain of Fibronectin.
Developmental Biology
136:
97103.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1989. Genetic engineering as metaphysics and menace.
Science and Nature
9/10:
113124.
Newman, S.A. 1988. Lineage and pattern in the developing vertebrate limb.
Trends in Genetics
4:
329332.
Newman, S.A. 1988. Idealist biology.
Perspectives in Biology and Medicine
31:
353368.
Newman, S.A.
1988. Human genetic engineering: Who needs it, and does it have a scientific basis? Working Paper BT-1 of the Institute for Philosophy and Public Policy, University of Maryland, College Park, MD.
Newman, S.A.
1988. Statement on proposed uses of human fetal tissue. In 'Report of the Human Fetal Tissue Transplantation Research Panel' Vol. II: Statements of Consultants to the Advisory Committee to the Director, National Institutes of Health, Bethesda, MD.
Newman, S.A./Frisch, H.L./Percus, J.K. 1988. On the stationary state analysis of reaction-diffusion mechanisms for biological pattern formation.
Journal of Theoretical. Biology
134:
183197.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A./Frenz, D.A./Tomasek, J.J./Rabuzzi, D.D. 1985. Matrix-driven translocation of cells and nonliving particles.
Science
228:
885889.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1984. Vertebrate bones and violin tones: Music and the making of limbs.
The Sciences
24:
3843.
Newman, S.A. 1984.
Embryonic development as a mode of activity of the living state: The case of the vertebrate limb.
In
Mishra, The Living State,
323335.
Newman, S.A./Leonard, C.M. 1983.
Against programs: Limb development without developmental information.
In
Fallon/Caplan, Limb Development and Regeneration,
251266.
Newman, S.A. 1982. The scientific selling of recombinant DNA.
Environment
24:
2123; 53÷57..
Newman, S.A. 1981. The politics of biological determinism.
Appeal to Reason
6:
7684.
Newman, S.A./Frisch, H.L./Perle, M.A./Tomasek, J.J. 1981.
Limb development: Aspects of differentiation, pattern formation and morphogenesis.
In
Connelly/Brinkley/Carlson, Morphogenesis and Pattern Formation,
163178.
Newman, S.A. 1980. Fibroblast progenitor cells of the embryonic chick limb.
Journal of Embryology and Experimental Morphology
56:
191200.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1979. The Un Body: A Possible Structure for Transcriptionally Inactivated Chromatin Subunits.
Journal of Theoretical Biology
79:
5566.
Keywords:
biochemistry
molecular biology.
Newman, S.A./Frisch, H.L. 1979. Dynamics of skeletal pattern formation in developing chick limb.
Science
205:
662668.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A.
1978. Biohazards of recombinant DNA Technology. In Regulation of Recombinant DNA Research: Hearings before the Subcommittee on Commerce, Science and Transportation of the U.S. Senate. Serial No. 95-52, U.S. Government Printing Office, Washington, 388390.
Newman, S.A. 1977.
Lineage and pattern in the developing wing bud.
In
Ede/Hinchliffe/Balls, Vertebrate Limb and Somite Morphogenesis,
##.
Newman, S.A./Birnbaum, J./Yeoh, G.C.T. 1976. Loss of a non-histone chromatin protein parallels In vitro differentiation of cartilage.
Nature
259:
416418.
Keywords:
biochemistry
molecular biology.
Newman, S.A. 1974. The interaction of the organizing regions in Hydra and its possible relationship to the role of the cut end in regeneration.
Journal of Embryology and Experimental Morphology
31:
541555.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1973. Reversible abolition of normal morphology in Hydra.
Nature New Biology
244:
126128.
Keywords:
cell differentiation
morphogenesis
pattern formation.
Newman, S.A. 1972. A source of stability in metabolic networks.
Journal of Theoretical Biology
35:
227232.
Keywords:
complex systems
metabolic regulation.
Newman, S.A. 1972.
The qualitative dynamics of enzyme networks.
In
Harris/Allin/Viza, Cell Differentiation,
300305.
Newman, S.A./Rice, S.A. 1971. A model for constraint and control in biochemical networks.
Proceedings of the National Academy of Sciences USA
68:
9296.
Keywords:
complex systems
metabolic regulation.
Newman, S.A. 1970. Note on complex systems.
Journal of Theoretical Biology
28:
411413.
Keywords:
complex systems
metabolic regulation.
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